{"id":620,"date":"2025-05-28T18:44:45","date_gmt":"2025-05-28T16:44:45","guid":{"rendered":"https:\/\/path-for-young.unicancer.fr\/?page_id=620"},"modified":"2025-07-04T17:54:02","modified_gmt":"2025-07-04T15:54:02","slug":"ambition-of-the-path-for-young-project","status":"publish","type":"page","link":"https:\/\/path-for-young.unicancer.fr\/es-ar\/path-for-young\/ambition-of-the-path-for-young-project\/","title":{"rendered":"Ambition of the Path-for-young Project"},"content":{"rendered":"\n<div class=\"wp-block-uagb-container uagb-block-d2d86a66 alignfull uagb-is-root-container\"><div class=\"uagb-container-inner-blocks-wrap\"><div class=\"plmb plmb-text mce-content clearfix format-intro\">\r\n\t<h1>Ambition of the<br \/>\nPath-for-young Project<\/h1>\n<\/div>\r\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-770e52a0 alignwide uagb-is-root-container\">\n<div class=\"wp-block-uagb-container uagb-block-158db01b\"><div class=\"plmb plmb-text mce-content clearfix format-classic resp-format-mob-left\">\r\n\t<h2 style=\"text-align: right\"><span style=\"font-size: 20px\">The main ambition of <\/span><br \/>\n<span style=\"font-size: 20px\">Path-for-young is to set and implement a new Standard of Care (SoC) for premenopausal patients with high-risk HR+HER2-BC. Using a stratification strategy, Path-for-young will:<span class=\"Apple-converted-space\">\u00a0<\/span><\/span><\/h2>\n<\/div>\r\n<\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-918e1905\"><div class=\"plmb plmb-text mce-content clearfix format-classic\">\r\n\t<ul>\n<li>predict benefit from chemotherapy for<\/li>\n<li>premenopausal patients,<\/li>\n<li>personalize adjuvant treatment choices,<br \/>\nprevent quality of life deterioration by avoiding long-term treatment-related effects,<\/li>\n<li>improve supportive care strategies including better utilization of digital health tools, and<\/li>\n<li>integrate the participation of patients during conceptualization and implementation of the project.<\/li>\n<\/ul>\n<p><b>Additionally, the project aims to provide the following results.<span class=\"Apple-converted-space\">\u00a0<\/span><\/b><\/p>\n<\/div>\r\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-f7ab8ff4 alignfull uagb-is-root-container\"><div class=\"uagb-container-inner-blocks-wrap\">\n<div class=\"wp-block-uagb-container uagb-block-78a0feba\"><\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-7c832ee6\"><div class=\"plmb plmb-text mce-content clearfix format-classic\">\r\n\t<h2>For patients and<br \/>\nthe general population<\/h2>\n<ul>\n<li style=\"list-style-type: none\">\n<ul>preservation and improvement of several domains of quality of life among premenopausal survivors of BC,<\/ul>\n<\/li>\n<li>improved adherence to ET,<\/li>\n<li>better understanding how to support premenopausal women with a diagnosis of early stage, higher risk breast cancer by promoting the implementation of personalized survivorship medicine and facilitating patient empowerment along the pathway of care,<\/li>\n<li>promotion of a process of co-creation and co-design of clinical trials and interventions with key stakeholders, including patient<\/li>\n<li>more accurate information about treatment pathways.<\/li>\n<\/ul>\n<\/div>\r\n<\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-311ea660 alignfull uagb-is-root-container\"><div class=\"uagb-container-inner-blocks-wrap\">\n<div class=\"wp-block-uagb-container uagb-block-e501d367\"><div class=\"plmb plmb-text mce-content clearfix format-classic\">\r\n\t<h2><span style=\"color: #00b8b5\">For the general<br \/>\nhealth care professionals<\/span><\/h2>\n<ul class=\"green-list\">\n<li>access to improved clinical recommendations and therapeutic decisional tools better understanding of the benefit derived by breast cancer patients from adjuvant CT,<\/li>\n<li>better understanding of the benefit derived by breast cancer patients from adjuvant CT,<\/li>\n<li>better understanding of the patient experience, process of therapeutic choices,<\/li>\n<li>better understanding of how to support patients,<\/li>\n<li>increased awareness of personalized, predictive, proactive, participatory, and psychocognitive medicine.<\/li>\n<\/ul>\n<\/div>\r\n<\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-271662b3\"><\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-decbcc60 alignfull uagb-is-root-container\"><div class=\"uagb-container-inner-blocks-wrap\">\n<div class=\"wp-block-uagb-container uagb-block-8d33ff43\"><div class=\"plmb plmb-text mce-content clearfix format-classic\">\r\n\t<h2>For decision makers and health authorities<\/h2>\n<ul class=\"ocean-list\">\n<li style=\"list-style-type: none\">\n<ul class=\"ocean-list\">provision of scientific evidence and multi-national HTA including robust cross-country cost-economic analysis of multiparameter assay driven treatment strategies,<\/ul>\n<\/li>\n<li>demonstration of the feasibility of implementation of a personalized non-invasive diagnostic driven strategy on a global scale,<\/li>\n<li>identification of adequate care pathways models for the delivery of optimal care for premenopausal patients with high-risk BC.<\/li>\n<\/ul>\n<\/div>\r\n<\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-b00ff260\"><div class=\"plmb plmb-text mce-content clearfix format-classic\">\r\n\t<h2>For the medical research community<\/h2>\n<ul>\n<li>creation of a sustainable digital research infrastructure to decentralise research, facilitating pragmatic approaches, data sharing and patient engagement, including fostering equity, inclusion, and diversity in clinical trials;<\/li>\n<li>promote the understanding and implementation of large pragmatic clinical trials and de-escalation trials.<\/li>\n<\/ul>\n<\/div>\r\n<\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-1bb655a8 alignfull uagb-is-root-container\"><div class=\"uagb-container-inner-blocks-wrap\">\n<div class=\"wp-block-uagb-container uagb-block-30c90a90\"><\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-b6fd5ff1\"><div class=\"plmb plmb-text mce-content clearfix format-classic\">\r\n\t<h2>For industry\/small and medium enterprises (SMEs)<\/h2>\n<p>Prospective development of new personalized digital patient companion promoting self-management by RESILIENCE (SME partner of the consortium). In addition, Path-for-young will foster the international use of KLINEO (second SME partner of the consortium), a tool to aid clinicians and patients screen and self-screen, respectively, for eligibility for clinical trial inclusion and foster connections with research teams, currently implemented at the French national Level. Additional SMEs will have the opportunity to benefit from the project, since it will open opportunities for ancillary exploitation of data collected, including validation of additional multiparameter gene expression assays, and building algorithms for risk stratification of long-term toxicities.<\/p>\n<p>The Consortium is engaging in discussions with Veracyte, provider of the Prosigna testing used in Optima-young (see Clinical Studies Annex for details), to ensure maximal industrial valorisation of the scientific results generated by the project. If successful, this project will open new market opportunities to Prosigna and similar tests.<\/p>\n<\/div>\r\n<\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-3703e03e alignwide uagb-is-root-container\">\n<div class=\"wp-block-uagb-container page-nav-blue uagb-block-b277c911\"><div class=\"plmb plmb-image image-style-none\">\r\n\t\t<figure style=\"width:80px\">\r\n\t\t<div class=\"image-wrapper\" style=\"height:80px\"><img loading=\"lazy\" decoding=\"async\" width=\"1\" height=\"1\" src=\"https:\/\/path-for-young.unicancer.fr\/wp-content\/uploads\/2025\/05\/left-arrow.svg\" class=\"attachment-fhd size-fhd\" alt=\"previous page\" \/><\/div>\t<\/figure>\r\n\t\t<\/div>\r\n\n\n<div class=\"plmb plmb-text mce-content clearfix format-light-margin-title\">\r\n\t<h3 style=\"text-align: left\"><span style=\"font-size: 25px\">Path-for-young<\/span><\/h3>\n<\/div>\r\n<a class=\"spectra-container-link-overlay\" rel=\"noopener\" href=\"https:\/\/path-for-young.unicancer.fr\/path-for-young\/\"> <\/a><\/div>\n\n\n\n<div class=\"wp-block-uagb-container page-nav-green uagb-block-00ee5efe\"><div class=\"plmb plmb-image image-style-none\">\r\n\t\t<figure style=\"width:80px\">\r\n\t\t<div class=\"image-wrapper\" style=\"height:80px\"><img loading=\"lazy\" decoding=\"async\" width=\"1\" height=\"1\" src=\"https:\/\/path-for-young.unicancer.fr\/wp-content\/uploads\/2025\/05\/left-arrow.svg\" class=\"attachment-fhd size-fhd\" alt=\"previous page\" \/><\/div>\t<\/figure>\r\n\t\t<\/div>\r\n\n\n<div class=\"plmb plmb-text mce-content clearfix format-light-margin-title\">\r\n\t<h3 style=\"text-align: left\"><span style=\"font-size: 25px\">Objectives<br \/>\nof the\u00a0project<\/span><\/h3>\n<\/div>\r\n<a class=\"spectra-container-link-overlay\" rel=\"noopener\" href=\"https:\/\/path-for-young.unicancer.fr\/path-for-young\/objectives-of-the-path-for-young-project\/\"> <\/a><\/div>\n\n\n\n<div class=\"wp-block-uagb-container page-nav-beige uagb-block-3af345e6\"><div class=\"plmb plmb-image image-style-none\">\r\n\t\t<figure style=\"width:80px\">\r\n\t\t<div class=\"image-wrapper\" style=\"height:80px\"><img loading=\"lazy\" decoding=\"async\" width=\"1\" height=\"1\" src=\"https:\/\/path-for-young.unicancer.fr\/wp-content\/uploads\/2025\/05\/right-arrow.svg\" class=\"attachment-fhd size-fhd\" alt=\"next page\" \/><\/div>\t<\/figure>\r\n\t\t<\/div>\r\n\n\n<div class=\"plmb plmb-text mce-content clearfix format-light-margin-title\">\r\n\t<h3 style=\"text-align: right\"><span style=\"font-size: 25px\">Patient engagement<br \/>\nand representation<\/span><\/h3>\n<\/div>\r\n<a class=\"spectra-container-link-overlay\" rel=\"noopener\" href=\"https:\/\/path-for-young.unicancer.fr\/patient-engagement-and-representation\/\"> <\/a><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":526,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","_analytify_skip_tracking":false,"footnotes":""},"class_list":["post-620","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - 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